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Creators/Authors contains: "Brock, Kristy K"

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  1. Free, publicly-accessible full text available December 1, 2026
  2. Given the enormous output and pace of development of artificial intelligence (AI) methods in medical imaging, it can be challenging to identify the true success stories to determine the state-of-the-art of the field. This report seeks to provide the magnetic resonance imaging (MRI) community with an initial guide into the major areas in which the methods of AI are contributing to MRI in oncology. After a general introduction to artificial intelligence, we proceed to discuss the successes and current limitations of AI in MRI when used for image acquisition, reconstruction, registration, and segmentation, as well as its utility for assisting in diagnostic and prognostic settings. Within each section, we attempt to present a balanced summary by first presenting common techniques, state of readiness, current clinical needs, and barriers to practical deployment in the clinical setting. We conclude by presenting areas in which new advances must be realized to address questions regarding generalizability, quality assurance and control, and uncertainty quantification when applying MRI to cancer to maintain patient safety and practical utility. 
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    Free, publicly-accessible full text available April 9, 2026
  3. Abstract Image segmentation of the liver is an important step in treatment planning for liver cancer. However, manual segmentation at a large scale is not practical, leading to increasing reliance on deep learning models to automatically segment the liver. This manuscript develops a generalizable deep learning model to segment the liver on T1-weighted MR images. In particular, three distinct deep learning architectures (nnUNet, PocketNet, Swin UNETR) were considered using data gathered from six geographically different institutions. A total of 819 T1-weighted MR images were gathered from both public and internal sources. Our experiments compared each architecture’s testing performance when trained both intra-institutionally and inter-institutionally. Models trained using nnUNet and its PocketNet variant achieved mean Dice-Sorensen similarity coefficients>0.9 on both intra- and inter-institutional test set data. The performance of these models suggests that nnUNet and PocketNet liver segmentation models trained on a large and diverse collection of T1-weighted MR images would on average achieve good intra-institutional segmentation performance. 
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  4. Free, publicly-accessible full text available June 1, 2026